Diet Similar To Fasting Might Help MS

What we eat can make a huge difference in how we feel; what we don’t eat can also have an impact. Although there is no one multiple sclerosis (MS) diet, there are several different approaches to eating that might make a difference with the disease.

Researching how diet affects health is not an easy task and often starts with studies involving animals. Researchers will often use a mouse model of MS called experimental autoimmune encephalomyelitis (EAE) to test how different interventions affect the immune system or disease symptoms. In the MS community, we often joke that it is the mice that get all the cures. Translating their cures into human treatments has been a huge challenge.

Researchers at the University of Southern California investigating the role of diet interventions in MS found that a fasting-mimicking diet (FMD) promotes neuro-regeneration, reduces autoimmunity, and reduces symptoms in a mouse model of MS. They found that the FMD reduced the severity of clinical symptoms in all study mice and completely reversed symptoms in 20 percent of the animals. The improvements seen with FMD were associated with reduced levels of pro-inflammatory cytokines, increased corticosterone levels, and increased production of oligodendrocyte cells that encouraged remyelination (Choi et al, 2016).

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Diet That Mimics Fasting May Reduce MS Symptoms

Is There An MS Diet?

How might diet have an effect on MS?

What you eat may have a direct effect on the immune system. The National MS Society shares that “recent immunological research has shown that metabolism plays an important role in the function of several types of immune cells,” with receptors for dietary metabolites, such as vitamin D or fatty acids, found on immune cells. Food may have an indirect effect on the immune system through modulation of gut flora, shifting the immune system towards a pro- or anti-inflammatory state.

Research is investigating the effects of diet and altered metabolism on the central nervous system. Various foods and diets are being studied for their effects on cellular components of the central nervous system such as neuron and glial cells. Diets could have a beneficial role by providing factors that could protect these important cells. 

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MS Diet and Nutritional Approaches to Treatment

Carnival of MS Bloggers #159

Welcome to the Carnival of MS Bloggers, a monthly compendium of thoughts and experiences shared by those living with multiple sclerosis.

Gut health

from MirandasMSBlog

Bacteria and Digestion

I quite often get asked about bloating. But did you know that you don’t have to have digestive symptoms to be suffering from ‘dysbiosis’ or wrong bacteria in the gut? It might be easy to think of this as something that’s just a minor inconvenience. However – gut problems are not just miserable & uncomfortable, they can also possibly play a role in auto-immune diseases like MS. In fact Hippocrates, the ‘Father of modern medicine’ is quoted as saying that ‘all disease begins in the gut’.

If the health of the gut breaks down, undigested food molecules can pass into the bloodstream. This is known as ‘leaky gut’. These undigested food molecules can be interpreted by the body as ‘bad guys’, and activate an immune reaction, causing a food intolerance. According to the theory of ‘molecular mimicry’, the confused immune system can then mistake other molecules, of the body’s own tissues, which are similar to these undigested food molecules, to also be ‘bad guys’ or pathogens, and launch an immune response to its own tissues, setting up an auto-immune disease.

So let’s take a look at this one aspect of gut health; bacteria, & how it affects us. The gut is basically a long tube, that travels from the mouth to the anus, with many shapes & sizes along the way, to accommodate the different stages of digestion! I’ve discussed constipation, diet and stool health, and the link between auto-immune disease and food intolerances before in this blog , but today I’m thinking about the tiny beings who live with us, lovingly help to keep us healthy but also depend on us too for their existence – Bacteria! bacteria


From the 1600s, and the invention of the first microscope, we have known about the existence of our internal bacteria, but up until quite recently, the focus for medicine has been more about the ‘war on germs’, and the eradication of infectious disease. We now understand that our gut is home to approximately 100 trillion micro-organisms. Did you know that: Bacterial cells outnumber our human cells to the extent that you could say that we are actually only 10% human, and 90% bacterial? Or that three pounds of your body weight is bacteria?

75% of our immune system is comprised of intestinal bacteria – and it also helps to regulate metabolism, digestion and the absorption of nutrients from food. The health of our gut depends on this intestinal ‘flora’ being in balance, and gut health is critical to overall health, with poor gut health implicated in a wide range of diseases including diabetes, obesity, rheumatoid arthritis and other auto-immune diseases, autism spectrum disorder and even depression. So what can disrupt the healthy bacteria in the gut? Top of the list is

• Antibiotics – life saving but also seriously disrupt the ‘biome’

Amongst others,

• Steroids and other medications like birth control and non- steroidal anti-inflammatories
• Diets high in refined carbohydrates, sugar and processed foods
• Diets low in ‘fermentable fibres’ – food for the good bacteria
• Chronic stress and Chronic infections

What can we do to help repopulate the gut with healthy bacteria? And what to do if suffering from ‘digestive discomfort!’?

• Eat plenty of fermentable fibers (sweet potato, Jerusalem artichoke, yams, dandelion greens, leeks, onion, garlic, or bananas) or take a pro-biotic ( good bacteria) capsule that includes Pre-biotics ( food for the good bacteria)
• Eat fermented foods like kefir, live yogurt,( be aware these 2 are dairy based), kombucha, sauerkraut, kim chi, – traditionally most societies do, but we’ve forgotten to!
• and/or take a high-quality, MULTI-STRAIN PRO-BIOTIC ( good bacteria) capsule daily – Bio-Kult is a good one, many others too
• Keep your diet as close to whole foods as possible
• Learn how to manage stress healthily

Taking regular probiotics helps to re-establish the strength of our gut and digestion, reducing the incidence of food intolerances, and allowing the body to free up more of its energy for healing painful conditions. It has also been found to help prevent recurrent infections like urine infections, and increase our ability to fight off the bad bacteria. The cheapest dairy-free way to get good bacteria into your diet is by making your own sauerkraut – It’s super easy to make – just get a head of organic cabbage, chop it up, punch it in a bowl, sprinkle salt on it, let it sit for half an hour, then put it in jars with a bit of salt water and let it sit on your kichen top for a week. There’s loads of instructions on the internet, but that’s about the size of it. Then use it like pickle. Til next time :)


This concludes the 159th edition of the Carnival.  The next Carnival of MS Bloggers will be hosted here on October 2, 2014. Please remember to submit a post (via email) from your blog of which you are particularly proud, or which you simply want to share, by noon on Tuesday, September 20, 2014.

Comments for this post.

Simple Taco Salad

The key to this salad is the cooked kidney bean and vegetable mixture.  A few years ago in the frozen food section, I discovered Hanover Latino Blend Vegetables (16 oz. bag) which includes corn, black beans, onions, green peppers, and red peppers.  This combination of vegetables is perfect for a taco salad.  Cooking/frying the kidney beans in salt and pepper changes the flavor in a way that compliments the salad.

The following recipe usually feeds 3 people in our household.  The kidney beans are high in fiber.  The romaine lettuce, tomatoes, and mixed vegetables are low in calories.  The cumin enhances the mexican flavor, as does the salsa and cheddar jack cheese.  The optional honey french dressing adds a little sweetness to accompany the salty of the kidney beans.

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Favorite Recipe: Taco Salad with Kidney Beans, Latino Vegetables, and Salsa

Carnival of MS Bloggers #123

Welcome to the Carnival of MS Bloggers, a bi-weekly compendium of thoughts and experiences shared by those living with multiple sclerosis.

FDA Approves MS Pill, MS Inconvenience, 
and Anti-inflammatory Foods to Help MS

FDA approves oral drug, Aubagio (teriflunomide), for treatment of Relapsing MS 

from Lisa Emrich of Brass and Ivory: Life with MS and RA 

Late Wednesday afternoon, the FDA announced that Aubagio (teriflunomide) has been approved for adults with relapsing forms of MS.  Click through to the original blog post to find the FDA announcement, a Reuters news report, abstracts for 12 academic studies published between 2006 and 2012 regarding teriflunomide and oral medications in development for MS, and the Genzyme press release regarding the FDA approval of Aubagio (teriflunomide).

GRRRRR!! 

from Stax of Multiple Sclerosis & Me

i hate being sick; having MS!!

that's all; no funny stories, no lamenting or feeling sorry for myself. i just hate it; it's a pain in my ass and a big inconvenience.

What to eat with MS? 

from The Girl With MS 

Nutrition will allow you to Thrive with MS! Anyone with MS should know what cooling foods are and how they affect the body and the disease.

My research began over ten years ago. Three different Chinese medicine doctors diagnosed me as being kidney yen deficient. While investigating what these doctors were telling me, I found that many of the symptoms for this 5,000 year old Chinese disease were shockingly similar to that of modern day MS and many autoimmune diseases for that matter.

When asked about the cause the Chinese doctors all responded with "Western diet and lifestyle". The Western diet contains many processed and falsely seasoned foods not to mention excess fat. Western people are known to skip meals, eat on the hoof and gorge on salte, fat and sweets with no care about their bodies.

According to Chiness Medicine there are different kinds of food: cool, neutral and heating. Depending upon our makeup and health dictates which foods are best. For an inflamed person with MS the cooling foods are desired.

(FYI - Chinese Medicine offers much more than discussed here where it's been crudely simplified. Resources linked below)

So what foods cool off the body and help my MS?


Some obvious food such as cucumbers come to mind. Apples, bananas, citrus, clams and many more. But what about sushi? Have you ever eaten the eel? Unagi? One summer there was a heat wave in Japan and a subsequent shortage of Unagi due to its cooking effect on the body.

Imagine using foods to cool off and saving that electricity bill!

Information about cooling foods and nutrition for MS has grown significantly these
past ten years. Here are some places to check out:

A good primer on Chinese Medicine and food classifications

Spreadsheet of foods by class from DocStock

Heating vs Cooling Foods. A review

Food as Medicine - a look into Chinese Medicine. (downloadable PDF)

Chinese Food Pyramid for Dogs and More

Nutrition will allow you to Thrive with MS!

This concludes the 123rd edition of the Carnival.  The next Carnival of MS Bloggers will be hosted here on September 27, 2012. Please remember to submit a post (via email) from your blog of which you are particularly proud, or which you simply want to share, by noon on Tuesday, September 25, 2012.

Thank you.

Comments for this post.

Carnival of MS Bloggers #114

Welcome to the Carnival of MS Bloggers, a bi-weekly compendium of thoughts and experiences shared by those living with multiple sclerosis.

Powerful Food, Pseudoexacerbations, and B/B Dysfunction

Unmentionable Bits

by Webster of halt stop forget relax

I imagine that many of you with MS deal with the dreaded B&B issue; not the second B - Bladder - which gets lots of attention. We either pee too often, or not enough, or get UTIs all the time, or wet our bed, or our pads, or ourselves. But the first B - Bowel - is the one that rarely gets talked about, and when it does get talked (or written about in neat little pamphlets explaining the various symptoms of MS that may affect us) it leans toward one end of the spectrum -- constipation. Oh, the dreaded bloating and feeling that you have to take a dump, but you just can't.

It doesn't tell you that constipation can be so bad that you need to see a gastroenterologist to find ways to manage it. Like taking doses of various meds, laxatives, eat more fiber, or even using your fingers to pry the stool from you. Oh happy, oh joy. Of course, you know you might be able to go if you just drank enough water to wash things out, but when you do that you can't control the other B [Bladder] (see paragraph one.)

It also doesn't tell you about the other problem: incontinence. Yes, that kind of incontinence. Going without warning wherever you might be. I have known someone to whom that happened - in a high end department store, no less. The sales clerks were very kind to her and led her to a private bathroom so she could clean up, and brought her a change of clothes. Yes, they were very kind indeed. She never set foot in that store again.

They don't mention that in those pamphlets. N'uh uh. And another woman told me that she was in a mall when it happened to her; suddenly it started running down her leg. She said she never wanted to be a runner, but she did that day. She was mortified, and lucky too, in a way, because though  she left a trail of sorts, it just led to an empty parking spot. She retained her anonymity, at least.

What if the problem you have is that you can't feel when you have to go until, well, until it's actually TIME TO GO? And what if that happens when you're in the middle of a dream that starts telling you to get to a bathroom ... any bathroom ... like right now? And you wake up in a stupor, and you can barely move your legs because the blankets were a little too warm and you try to stand up, and you can't? You try and you try and you keep falling back onto the bed, and you start going and you know you can't control it? What do you do? This is no nightmare; well, yes it is, it is a nightmare, and this nightmare is part of MS. This is what happened to me the night before last.

So I look around to see what I have nearby that might save the situation. I find one of those thin blue plastic absorbent lined pads that they use at every urologist appt. [Don't mock me- I think it's foolish to  let all that Dr. office stuff go to waste - so I bring it home; you never know when it might come in handy] This seemed like the perfect thing to use it for - to catch my poop unmentionable bits so they didn't get all over my sheets. I turned to lay on my side and managed to get it beneath and behind me. My sheets were saved; I just lost my dignity as I had to call my husband to help at that point. I had no TP. I couldn't clean myself. I still couldn't stand. I was exhausted. I just wanted to cry but couldn't thanks to my antidepressant.

I needed more sleep, so after DH cleaned things up (he's so good, he takes these things in stride), I took a long nap, after which I was able to (barely) stand, at least enough to use a walker to go to the bathroom, take a shower and get dressed.

MS just keeps getting better and better. I know; you don't have to say it, I was happy to share.

[Here is more information regarding bowel dysfunction.]

Kale, the New Frontier

by Yvonne Sousa

Kale is the new black

I cannot put it off any longer. For almost forty years I have been shirking my vegetable consuming responsibilities and now it is time to face them. Don’t get me wrong, I would try to lean towards healthy eating often enough. If I decided to treat myself with a bit of fudge I always went for the pumpkin or cranberry variety to get some of my fruit requirement in.

When picking out ice cream flavor I would choose a vanilla base- vanilla being a type of bean. If went out to eat and was asked which side I would like with my entrée I would pick the French fries to get potatoes (a veggie after all) in with the meal. And, of course, I never held the lettuce, onion, or tomato on my burger. The pickles I would toss aside, you can only go so far on the health kick.

But for some reason all of the hard work above was not enough. Apparently I needed to take a more thorough and active stance on eating vegetables in their natural form. I have been told that they are a necessary part of the diet and eating more of them will help my health and my BMI. But as someone who has taken great pains to avoid them whenever possible, where to begin?

I like the idea of corn- well cornfields anyway. They present such a nice image of middle-America and kids with overalls and ribbons frolicking in the fields. But a super healthy cousin who has a small farm in her backyard (too weird, even for my family, a farm in Massachusetts,) informed me that corn is now the root of all evil.

Seems, she insists, that we Americans eat too much corn and give too much of it to our livestock and that is why we are falling apart. I guess that is good news. It is only the idea of corn that I like, the actual stuff is icky.

Ok, I can handle a salad. I will go with that. But no, it turns out iceberg lettuce is really just a big clump of green water. It is not that healthy, the experts are starting to say.

I was about to give up when a friend directed me to Dr. Terry Wahls website that shows a super good-for-you eating plan, designed especially for people with multiple sclerosis. At first, it was terrifying. Dr. Wahls wants you to eat nine cups of green leafy vegetables a day! That just seemed insane and totally overwhelming.

But I was committed so I continued exploring. One of the veggies she recommends is spinach. Well, I can kind of deal with that. Especially if I use the bagged, dry spinach and load it with dressing in order to pretend it is salad. That might work for me. The wet stuff Popeye used to chug is out of the question but maybe I could accept the dry stuff.

Then Dr. Wahls said something wonderful, something I could totally work with. It turns out that kale is a green leafy full of all kinds of nutrients and good stuff! Wow, I thought only Portuguese people knew about kale.

And I had no idea it was a vegetable! Is Dr. Wahls sure about this? I always thought kale was just a soup additive that you got from your grandmother’s house or your cousin’s yard (oh yeah, a farm, now I get it).


This whole time it seems we Portuguese folks were already on the health track! I did some more research and it turns out that kale is the new black, meaning, it is the new super food. And since it is super good for ms’ers, it is the new orange as well. Yay!

It shouldn’t surprise me that my Portuguese friends and family were leading the way in this regard. Didn’t our Brazilian cousins discover last year’s new super food- the Acai berry? Who knows what we will discover next? Maybe the delicious Portuguese pastry trutas are the next super food? Why not? Trutas are filled with sweet potato so there you go! We Portuguese folks have now discovered three new super foods.

What about codfish cakes? The poor cod is one ugly fish but he is a fish and so maybe filled with good proteins and stuff. Hey, I bet he eats kale too so if you eat codfish cakes you might be getting protein AND a vegetable.


And then there is the wine. I don’t care what the French or the Napa Valley people say, the best wine comes from Portugal. And, research shows that red wine is really good for you. The experts suggest drinking it in moderation but I know a lot of other experts that drink it all day and they seem pretty healthy. They are pretty vocal and animated at least.

I guess my dad knew what he was doing when we visited his homeland when I was twelve and he wouldn’t let me drink American soda. “You are in Portugal and will drink wine like all the other Portuguese kids!” I thought he was being weird. Turns out, he was just worried about my health.

Encouraged and energized, I set out to start my new healthy eating plan and the world fell into place! A nice, hot bowl of kale soup filled with all things good. Vegetables- kale-who knew, potatoes, and a tiny bit of carrots to give the soup some extra color (carrots are no longer one of the best veggies and I don’t want to muck up the soup up too badly), beans-this soup just gets healthier and healthier, linguica- protein, thank you, and salt pork.

I don’t know too much about salt pork- is it a vegetable too? Even if it is not it just adds a bit flavor so how bad can it be? Red wine, some Portuguese bread- hello-grains, butter- dairy of course, codfish cakes as a side- all kinds of health benefit there, and trutas for dessert. Repeat this meal nine times a day. I love Dr. Wahl. This is going to be a cinch!

It's Just Bacteria

by Sarah O

Don’t you sometimes have that feeling that you know exactly what your body is going through, what the problem is and where the problem is. Sometimes you really don’t have a clue. But sometimes you just know.


Another one of those weeks when you’re going through so much you don’t know what to control or where to start. Can’t say what triggered it. I do vaguely recall saying that my throat was hurting.  Then it wasn’t. Was going back and forth between the hospital to see an unwell relative. Also took some probiotics to cure a stomach bug. Had a few bad nights of worsening chills. The days were marked with a constant supply of acetaminophen to keep functional. Realized I had low grade fever throughout the day and all the ugly things that come with it. Body aches, dehydration, burning eyes. Sneakily getting worse, my bones started to ache, my limbs became weaker and weaker. “I have an infection.” I can't explain but it felt like something running rampant in my body. Until one day I was sitting at work crying, my bones hurt so bad I felt they would break, I couldn’t put pressure on my legs or carry anything with my arms.  All my other pains crept up with a vengeance.  It was like a symphony, each one trying to out-do the other and make itself heard and noticed. The pins and needles, the stabbing, the aching, the crawling, and the shooting.

I did get a bit scared. It could be the Fibromyalgia, the Multiple Sclerosis, or the Osteopenia.

Of course I went to a few doctors, but we started an antibiotic course on our own.  The white blood cell count was high. Within a few days I was getting back to normal. I slept like a baby and my pains were gone.  I have had many, many bad infections in the past, but never such a bad experience of tiding through it. Okay, so I’ve had some pretty bad infections in my life. They’re really not so hard to wait through. But this time, it was crippling.

Two things: A quick look around the internet shows how MS patients are at an increased risk from infections. The immune system is already compromised and any minor infection can cause serious flare-ups of existing symptoms, sending you hurtling over the edge.

Also, if you look it up, it is suggested that you see your GP if you have Multiple Sclerosis or a weak immune system and develop any Respiratory Tract Infection (RTI). A simple course of antibiotics may pep you right back up. If you want, you may look up detailed studies on the subject; http://www.ncbi.nlm.nih.gov/pubmed/8534384.

As for me, I’ve never been so petrified of coughing, sneezing germ bags in my life. Also, I've started carrying a hand sanitizer, and graciously offer it to as many as will use it !!

[Lisa's note: Here is more information regarding infection and pseudoexacerbations.  When living with MS, developing an infection can cause symptoms to temporarily worsen.  It can be quite unpleasant, but it doesn't affect the course of your disease.]


This concludes the 114th edition of the Carnival.  The next Carnival of MS Bloggers will be hosted here on May 24, 2012. Please remember to submit a post (via email) from your blog of which you are particularly proud, or which you simply want to share, by noon on Tuesday, May 22, 2012.

Thank you.

Comments for this post.

Restaurants Expanding Choice

The New York Times has an article regarding restaurants on Long Island offering gluten-free items on their menus. This is an excellent move by the restauranteurs to serve the needs of customers with celiac disease and other wheat sensitivities.

I've not tried much gluten-free food as a replacement for wheat-based items, but I would try such a thing if given the option while eating out. This seems like a smart move to me and hope that other restaurants follow suit.

Many patients with multiple sclerosis find that they feel better when following a dairy-free and gluten-free way of eating, as is presented in the second news article below. It's nice to know that options are increasing.

Restaurants Offering Gluten-Free Options

By CAROLYN NARDIELLO

Published: July 20, 2008

A growing number of restaurants on Long Island have added gluten-free dishes to accommodate customers with celiac disease.

Going gluten-free -- for many reasons
By JANET CROMLEY, Los Angeles Times Staff Writer
Published: July 7, 2008
Diagnosed with celiac disease, or self-diagnosed. Sensitive to foods, or related to those who are. The gluten-free diet trend is getting a warm embrace.